In today’s supplement market, top-selling products promise everything from enhanced cognitive function to improved digestion and increased muscle mass. Among these, choline, betaine, and L-carnitine stand out as popular choices. Let’s explore these specific compounds and their impact on health.
While I support natural supplements and local vitamin stores, a common question arises: “Can’t I obtain these nutrients from food instead of supplements?” The answer is yes—choline, betaine, and L-carnitine are all found in high concentrations in animal-based foods such as meat, dairy, and eggs, while present in smaller amounts in plant-based foods. Let’s dive deeper into why this matters.
The Role of TMAO
When choline, betaine, and L-carnitine from animal products are metabolized by gut bacteria and liver enzymes, they convert into a compound called TMAO (Trimethylamine N-oxide). TMAO is a colorless amine oxide that accumulates in animal tissues. Research from the National Center for Biotechnology Information has linked elevated plasma levels of TMAO to an increased risk of cardiovascular disease and even mortality.
Further studies reveal that TMAO can also disrupt cholesterol and bile metabolism, triggering inflammation and potentially decreasing kidney function.
Conventional Solutions: Antibiotics and Drugs
One proposed solution to reduce TMAO levels is the use of antibiotics to eliminate the gut bacteria that convert choline, betaine, and L-carnitine into TMAO. However, antibiotics also destroy beneficial gut bacteria, which are vital for maintaining optimal health. In my experience, antibiotics should only be used in life-threatening situations due to their potential harm to the body’s microbiome.
Pharmaceutical scientists have also developed a drug designed to inhibit the liver enzyme that converts TMA (Trimethylamine) into TMAO. However, TMA is associated with a “fishy” body odor, making such a drug less appealing and practical for everyday use.
Plant-Based Alternatives: A Safe Solution
A common concern is whether plant-based foods like broccoli and Brussels sprouts, which also contain choline, lead to TMAO production. Research from Biochemical Pharmacology shows they do not. In fact, a study by Robert A. Koeth, published in Nature Medicine, demonstrated that omnivores produce more TMAO than vegans or vegetarians after consuming L-carnitine. This finding suggests a direct link between L-carnitine intake, gut bacteria, TMAO production, and an elevated risk of heart disease.
Optimal Solution: Embrace a Whole Foods, Plant-Based Diet
If you’re concerned about TMAO and its impact on your health, transitioning to a whole-foods, plant-based diet is a powerful step. By minimizing or eliminating animal products, you reduce exposure to the compounds that lead to TMAO production, supporting cardiovascular health and overall wellness.
Beyond reducing TMAO levels, a plant-based lifestyle offers countless benefits. It’s easier to implement and more rewarding than many realize, promoting overall vitality and long-term health.
Are you ready to take control of your health and explore the benefits of a plant-based lifestyle? Reach out for personalized support and guidance on your journey to wellness.
Be well always!
Cynthia Moon